JIDAM
"An Official Journal of IDA - Madras
Branch" ©2019.
Available online
Castleman's disease is a rare clinical entity presenting either as localised benign tumours affecting chiefly the lymph nodes or as widespread systemic disease. The incidence of castle man's disease occurring in the head and neck region is very rare and hence it is not much known. The disease is thought to be due to over production of Interleukin 6 or due to hyper responsiveness to Interleukin 6. Human herpes virus type 8 ( HHV -8) is also proposed to be associated with castle man's disease. The localized type is treated by simple surgical excision. Though recurrence is rare, the plasma cell type requires regular follow up. The multicentric type often requires aggressive systemic therapy with corticosteroids and has poor prognosis. In some patients, the multicentric disease has been associated with HIV infection. Here, we report a case of castle man's disease in a 32 year old male patient involving the masseter and sub mental region to emphasis the importance of including this disease in the differential diagnosis of swellings in the head and neck region.
Key words: Castleman's disease, masseter, sub mental region
JIDAM/Volume:6/Issue:1/Pages33-36/Jan-Mar 2019